Chlorhexidine beats povidone-iodine in preventing vascular catheter colonisation

An impressive randomised multi-centre study in Japan has evaluated the efficacy of 0.5 and 1% alcohol/chlorhexidine with 10% povidone-iodine in preventing colonisation of vascular catheters. The study concluded that chlorhexidine at either concentration is superior to povidone-iodine in preventing the colonisation of vascular catheters. The study was performed in 16 Japanese intensive care units. The 796 central…

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Chlorhexidine crosses the line ahead of the competition in preventing catheter related infections

A randomised controlled study with a clinical outcome compared the impact of chlorhexidine, octenidine, and povidone iodine used for cutaneous antisepsis for preventing line infections associated with intravascular catheters. Chlorhexidine knocked spots off the competition, with patients randomised to chlorhexidine significantly less likely to develop line-relates sepsis or bacterial contamination when compared with octenidine or povidone iodine.…

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